BS IS0 19463:2018 Bsl Standards Publication Microbeam analysis Electron probe microanalyser (EPMA) Guidelines for performing quality assurance procedures bsi. BSISO19463:2018 BRITISH STANDARD Nationalforeword This British Standard is the UK implementation of IS019463:2018. The UK participation in its preparation was entrusted to Technical Committee Cll/9, Microbeamanalysis. A list of organizations represented on this committee can be obtained on requestto its secretary. This publication does not purport to include all the necessary provisions of a contract. Users are responsible for its correct application. TheBritish Standards Institution2018 Published by BSI Standards Limited 2018 ISBN9780580856358 ICS71.040.50 Compliance with a British Standard cannot confer immunity from legal obligations. This British Standard was published under the authority of the StandardsPolicyand StrategyCommitteeon31July2018. Amendments/corrigendaissuedsincepublication Date Textaffected BS ISO 19463:2018 ISO INTERNATIONAL STANDARD 19463 First edition 2018-07-21 Microbeam analysis Electron probe microanalyser (EPMA) - Guidelines for performing quality assurance procedures AnalyseparmicrofaisceauxAnalyseparmicrosondeélectronique (microsondede Castaing)Lignesdirectricespourlamiseenceuvre desproceduresd'assurancequalite Reference number IS0 19463:2018(E) X ISO @IS02018 BSISO19463:2018 IS0 19463:2018(E) COPYRIGHTPROTECTEDDOCUMENT @ IS0 2018, Published in Switzerland All rights reserved. Unless otherwise specified, no part of this publication may be reproduced or utilized otherwise in any form or by any means, electronic or mechanical, including photocopying,or posting on the internet or an intranet, without prior written permission. Permission can be requested from either ISO at the address below or ISo's member body in the country of the requester. ISO copyright office Ch.de Blandonnet 8.CP 401 CH-1214 Vernier, Geneva, Switzerland Tel. +41 22 749 01 11 Fax +41 22 749 09 47 [email protected] www.iso.org ii ISO 2018-Allrights reserved BSISO19463:2018 IS019463:2018 Contents Page Foreword iv Introduction A 1 Scope .1 2 Normativereferences .1 3 Terms and definitions .1 4 Generalprinciples ofelectronprobemicroanalyserqualityassurance (EPMAQA) .6 4.1 Objective 6 4.2 Selection of challenge materials 6 4.2.1 General. 6 4.2.2 General characteristicsofanalysedmaterials 6 4.2.3 Specificcharacteristicsofchallengematerials 7 4.3 QAmeasurementparameters 7 4.3.1 General. 7 4.3.2 Laboratory environment preparation 7 Instrument parameters .8 4.3.3 4.4 Dataacquisition. 11 4.5 Frequency of QA diagnostic testing 12 5 Test report .12 6 Data analysis and performance tracking .13 6.1 General 13 6.2 Quantitativeanalysisofthechallengematerial .13 6.3 Calculation of means and standarddeviations .13 6.4 .13 Statisticaltestsperformedondata 6.4.1 13 General. 6.4.2 Normality test. 14 6.4.3 Variancetest .14 Annex A (informative)Examples ofchallengematerials and reference materials for EPMAWDSQA. .15 AnnexB (informative)Distinguishing specimenpreparation effectsfrom instrument .17 malfunction .21 AnnexC (informative)Graphicalrendering ofdata andcontrol charting .26 AnnexD (informative)Failure modes indicated bytestresults Bibliography .30 @ IS0 2018 - All rights reserved iii BSIS019463:2018 IS019463:2018 Foreword Iso (the International Organizationfor Standardization)is a worldwidefederation of national standards bodies (Iso member bodies). The work of preparing International Standards is normally carried out through IsO technical committees. Each member body interested in a subject for which a technical committee has been established has the right to be represented on that committee. International organizations,governmental and non-governmental, inliaison with Iso, also takepart in the work. ISo collaborates closelywith the International Electrotechnical Commission (IEC)on all matters of electrotechnical standardization. The procedures used to develop this document and those inte